The Role of Viscosupplementation

被引：32

作者：

Axe, Jeremie M. ^{[1
]}

Snyder-Mackler, Lynn ^{[2
]}

Axe, Michael J. ^{[2
]}

机构：

[1] Tufts Med Ctr, Boston, MA USA

[2] Univ Delaware, Dept Phys Therapy, Newark, DE USA

来源：

SPORTS MEDICINE AND ARTHROSCOPY REVIEW | 2013年 / 21卷 / 01期

关键词：

hyaluronic acid; middle-aged; intra-articular; corticosteroid; osteoarthritis; athlete; G-F; 20; INTRAARTICULAR HYALURONIC-ACID; KNEE OSTEOARTHRITIS; SYNOVIAL-FLUID; MOLECULAR-WEIGHT; HYLAN G-F-20; SODIUM HYALURONATE; CLINICAL-TRIAL; ARTHRITIS; EFFICACY;

D O I：

10.1097/JSA.0b013e3182673241

中图分类号：

G8 [体育];

学科分类号：

040301 [体育人文社会学];

摘要：

The treatment of early osteoarthritis in middle-aged athletes with intra-articular (IA) viscosupplementation using hyaluronic acid (HA) has been used since the late 1980s. Administration of IA HA has demonstrated anti-inflammatory, anabolic, and analgesic effects. Treatment of acute injuries such as anterior cruciate ligament reconstruction and full thickness chondral lesions have benefited with the addition of IA HA. Use of IA HA has also been shown to delay total knee arthroplasty. Although IA HA has shown significant benefits in the middle-aged athletes, it is not a ubiquitous treatment option. Success with corticosteroid injections can be used as a clinical marker for subsequent success with HA injections.

引用

页码：18 / 22

页数：5

共 72 条

[1]

The role of viscosupplenentation with hylan G-F 20 (Synvisc(R)) in the treatment of osteoarthritis of the knee: A Canadian multicenter trial comparing hylan G-F 20 alone, hylan G-F 20 with non-steroidal anti-inflammatory drugs (NSAIDs) and NSAIDs alone [J].