Amino acids in the syntheses of heterocyclic systems: Syntheses and radiostability of novel biologically active triazoles containing the sulfonamide moiety

被引：18

作者：

El-Sharief, AMS

Ghorab, MM

El-Gaby, MSA

Mohamed, SI

Ammar, YA

机构：

[1] Al Azhar Univ, Fac Sci, Dept Chem, Cairo, Egypt

[2] Natl Ctr Radiat Res & Technol, Dept Drug Radiat Res, Cairo, Egypt

[3] Al Azhar Univ, Fac Sci, Dept Chem, Assiut 71524, Egypt

来源：

HETEROATOM CHEMISTRY | 2002年 / 13卷 / 04期

关键词：

D O I：

10.1002/hc.10037

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

A number of novel triazoles 2a-f, 4, 9, 10, 12, 15; triazolothiadiazoles 6, 8, 11, 16; triazolothiadiazine 5; and triazolotriazine 14 were synthesized and characterized by elemental analyses and spectral data. Six of the compounds showed antifungal activity compared with the fungicide Mycostatine. Radiosterilization of the biologically active compounds 4, 8, 9b, and 10 in the dry state may prove to be applicable at the sterile dose 25 kGy. (C) 2002 Wiley Periodicals, Inc.

引用

页码：316 / 323

页数：8

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