Two new dammarane triterpene glycosides from the rhizomes of Panax notoginseng

被引:19
作者
Cui, Xiu-Ming [2 ,3 ]
Jiang, Zhi-Yong [1 ]
Zeng, Jiang [3 ]
Zhou, Jia-Ming [3 ]
Chen, Ji-Jun [1 ]
Zhang, Xue-Mei [1 ]
Xu, Luo-Shan [2 ]
Wang, Qiang [2 ]
机构
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China
[2] China Pharmaceut Univ, Nanjing 210009, Peoples R China
[3] Wenshan Prefecture Sanqi Res Inst, Wenshan, Yunnan, Peoples R China
关键词
Panax notoginseng; dammarane; triterpene glycosides; notoginsenoside Rw 1; notoginsenoside Rw 2;
D O I
10.1080/10286020802144776
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two new dammarane triterpene glycosides named notoginsenosides Rw 1 (1) and Rw 2 (2) were isolated from the rhizomes of Panax notoginseng, together with 20 known compounds including protopanaxadiol (3), protopanaxatriol (4), ginsenosides Rb1 (5), Rd (6), Re (7), Rg1 (8), Rg2 (9), 20-(S)-Rg3 (10), 20-(R)-Rg3 (11), Rh1 (12), Rh4 (13), Rf (14), 20-O-glucopyranosyl Rf (15), notoginsenosides R1 (16), R2 (17), T5 (18), S (19), T (20), and Fa (21), and koryoginsenoside R1 (22). Based on FABMS, HRFABMS, IR, 1H, 13C, and 2D-NMR (HSQC, HMBC, and COSY) spectral data, the structures of the new compounds were elucidated as 6-O--d-xylopyranosyl-20-O--d-xylopyranosyl-(16)--d-glucopyranosyldammar-24-ene-3,6,12,20(S)tetraol (1) and 6-O--d-xylopyranosyl-(12)--d-glucopyranosyldammar-22-ene-(trans)-3,6,12,20(S), 25-pentaol (2). Compounds 3, 4, 13, and 22 were isolated from P. notoginseng for the first time.
引用
收藏
页码:845 / 849
页数:5
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