Representing uncertainty: The role of cost-effectiveness acceptability curves

被引:812
作者
Fenwick, E [1 ]
Claxton, K
Sculpher, M
机构
[1] Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England
[2] Univ York, Dept Econ & Related Studies, York YO1 5DD, N Yorkshire, England
关键词
cost-effectiveness acceptability curves; cost-effectiveness acceptability frontiers; decision-making; net benefits; uncertainty;
D O I
10.1002/hec.635
中图分类号
F [经济];
学科分类号
02 ;
摘要
Decision-making in health care is inevitably undertaken in a context of uncertainty concerning the effectiveness and costs of health care interventions and programmes. One method that has been suggested to represent this uncertainty is the cost-effectiveness acceptability curve. This technique, which directly addresses the decision-making problem, has advantages over confidence interval estimation for incremental cost-effectiveness ratios. However, despite these advantages, cost-effectiveness acceptability curves have yet to be widely adopted within the field of economic evaluation of health care technologies. In this paper we consider the relationship between cost-effectiveness acceptability curves and decision-making in health care, suggest the introduction of a new concept more relevant to decision-making, that or the cost-effectiveness frontier. and clarify the use of these techniques when considering decisions involving multiple interventions. We hope that as a result we can encourage the greater use of these techniques. Copyright (C) 2001 John Wiley Sons, Ltd.
引用
收藏
页码:779 / 787
页数:9
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