Design of Magnetic Nanoparticles-Assisted Drug Delivery System

被引：27

作者：

Chen, Guo-Jing ^{[1
]}

Wang, Li-Fang ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Sch Life Sci, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan

来源：

CURRENT PHARMACEUTICAL DESIGN | 2011年 / 17卷 / 22期

关键词：

Nanotechnology; magnetic nanoparticles; superparamagnetic iron oxide; surface modification; targeting therapy; drug delivery; IRON-OXIDE NANOPARTICLES; CORE-SHELL NANOPARTICLES; ANIONIC SUPERPARAMAGNETIC NANOPARTICLES; RESPONSIVE CONTROLLED-RELEASE; I CLINICAL-EVALUATION; PHASE FLAME SYNTHESIS; GENE DELIVERY; SURFACE MODIFICATION; FE3O4; NANOPARTICLES; CONTRAST AGENTS;

D O I：

10.2174/138161211797052574

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Magnetic nanoparticles (MNPs) have been designed for multifaceted applications such as contrast agents in magnetic resonance imaging (MRI) diagnosis, drug/gene carriers for different kinds of therapeutic agents, tissue repair, hyperthermia, immunoassay, and cell separation/sensing. This review highlights synthesis methods, stabilizers used for surface coating on MNPs, and target ligands for ferrying payloads to an interested disease area. Some of the recent biomedical applications of MNPs in the field of drug and DNA targeting delivery are extensively reviewed.

引用

页码：2331 / 2351

页数：21

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