Boronic acid substituted viologen based optical sugar sensors: modulated quenching with viologen as a method for monosaccharide detection

被引：83

作者：

Camara, JN ^{[1
]}

Suri, JT ^{[1
]}

Cappuccio, FE ^{[1
]}

Wessling, RA ^{[1
]}

Singaram, B ^{[1
]}

机构：

[1] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(01)02366-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In our search for an optical glucose sensor we have found that the combination of pyranine I and a boronic acid substituted benzyl viologen (o-BBV. 2) signals in monosaccharides in the range of 0 1800 mg/dL. The quenching ability of o-BBV is modulated upon sugar binding. which in turn alters the fluorescence of pyranine. The system utilizes a dye that is active in the visible spectrum, operates in aqueous solution at pH 7.4, and is highly sensitive to glucose in the physiological range. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1139 / 1141

页数：3

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