The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virus-infected cell

被引:22
作者
Sjoberg, EM
Garoff, H
机构
[1] Karolinska Institute, Department of Biosciences at Novum
关键词
D O I
10.1099/0022-1317-77-6-1323
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We have recently shown that the Semliki Forest virus (SFV) subgenome contains a translation enhancer region in the coding part of its RNA. The enhnacer increases the translation of the viral structural genes approximately ten-fold and thereby plays a key role in virus assembly. In this study we conclusively show that this translation enhancer represents an adaptation to the (sic).
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页码:1323 / 1327
页数:5
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