Synthesis of the Gd(III) complex with a tetrazole-armed macrocyclic ligand as a potential MRI contrast agent

被引：22

作者：

Aime, S

Cravotto, G

Crich, SG

Giovenzana, GB

Ferrari, M

Palmisano, G

Sisti, M

机构：

[1] IFM, Dipartimento Chim, I-10125 Turin, Italy

[2] Dipartimento Sci & Technol Farmaco, I-10125 Turin, Italy

[3] Dipartimento Sci Chim Alimentari Farmaceut & Farm, I-28100 Novara, Italy

[4] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

[5] Dipartimento Sci Chim Fis & Matemat, I-22100 Como, Italy

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(01)02272-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the synthesis and the properties of the Gd(III) complex with 4 (H(4)dotetra), a novel mixed pendant-arm macrocyclic ligand embodying a tetrazole subunit in a N5O3 donor set as a potential magnetic resonance imaging (MRI) contrast agent. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：783 / 786

页数：4

共 30 条

[1] SYNTHESIS, CHARACTERIZATION, AND 1/T(1) NMRD PROFILES OF GADOLINIUM(III) COMPLEXES OF MONOAMIDE DERIVATIVES OF DOTA-LIKE LIGANDS - X-RAY STRUCTURE OF THE 10-[2-[[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]AMINO]-1-[(PHENYLMETHOXY)METHYL]-2-OXO-ETHYL]-1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID GADOLINIUM(III) COMPLEX [J].