Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces

被引：38

作者：

Gilbert, Jonathan B. ^{[2
]}

O'Brien, Janice S. ^{[1
]}

Suresh, Harini S. ^{[1
]}

Cohen, Robert E. ^{[2
]}

Rubner, Michael F. ^{[1
]}

机构：

[1] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA

[2] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 41期

基金：

美国国家科学基金会;

关键词：

polyelectrolyte multilayer; anisotropic; polymer; drug delivery; janus; MULTILAYER THIN-FILMS; DRUG-DELIVERY; POLYELECTROLYTE MULTILAYERS; NANOPARTICLES; NANOTUBES; DESIGN; PARTICLES; STRATEGIES; ANISOTROPY; THERAPIES;

D O I：

10.1002/adma.201302673

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Tubular particles presenting heterogeneous regions of chemistry on the tube-ends versus the side are fabricated and are shown to control the particle orientation on the surface of live lymphocytes. Controlling the orientation of anisotropic microparticles on cell surfaces is of interest for biomedical applications and drug delivery in particular, since it can be used to promote or resist particle internalization. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

收藏

页码：5948 / 5952

页数：5

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