Efficacy of quinolones against secondary pneumococcal pneumonia after influenza virus infection in mice

被引：6

作者：

Hayashi, K ^{[1
]}

Kadowaki, SE ^{[1
]}

Takei, M ^{[1
]}

Fukuda, H ^{[1
]}

机构：

[1] Kyorin Pharmaceut Co Ltd, Discovery Res Labs, Tochigi 3290114, Japan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 02期

关键词：

D O I：

10.1128/AAC.50.2.748-751.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We established a mouse model of secondary pneumococcal pneumonia after influenza virus infection and investigated the efficacy of several quinolones against pneumonia in this model. Gatifloxacin exhibited the highest efficacy among the quinolones examined and is probably useful for the treatment of secondary bacterial pneumonia.

引用

页码：748 / 751

页数：4

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