B-type natriuretic peptide levels in patients with paroxysmal lone atrial fibrillation

被引:35
作者
Li, Jingtian [1 ]
Wang, Lexin [1 ]
机构
[1] Charles Sturt Univ, Sch Biomed Sci, Wagga Wagga, NSW 2678, Australia
关键词
B-type natriuretic peptide; paroxysmal atrial fibrillation; left ventricular function;
D O I
10.1007/s00380-005-0884-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To investigate the levels of B-type natriuretic peptide (BNP) in patients with atrial fibrillation (AF) but without structural heart disease, we measured plasma BNP concentration in 61 consecutive AF patients and in 61 age- and sex-matched healthy subjects. Plasma BNP concentration in the AF group was significantly higher than in the control group (121 +/- 32 vs 41 +/- 12pg/ml, P < 0.001). Logistic regression analysis showed that age (r = 0.66, P < 0.001), left atrial diameter (r = 0.59, P < 0.01), and a history of AF (r = 0.72, P < 0.001) were independent predictors of elevated BNP. We concluded that BNP was elevated in patients with paroxysmal lone AF. The clinical significance of BNP elevation in these patients requires further investigation.
引用
收藏
页码:137 / 140
页数:4
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