Irreversible Protein Kinase Inhibitors: Balancing the Benefits and Risks

被引：254

作者：

Barf, Tjeerd ^{[1
]}

Kaptein, Allard ^{[1
]}

机构：

[1] Covalut Pharma BV, Drug Discovery Unit, Ravenstein, Netherlands

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2012年 / 55卷 / 14期

关键词：

GROWTH-FACTOR RECEPTOR; ATP-BINDING SITE; KAPPA-B-KINASE; TYROSINE KINASE; PHOSPHOINOSITIDE; 3-KINASE; CYCLOPENTENONE PROSTAGLANDINS; CYSTEINE RESIDUES; CATALYTIC DOMAIN; COVALENT-BINDING; STRUCTURAL BASIS;

D O I：

10.1021/jm3003203

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：6243 / 6262

页数：20

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