Correlative and mechanistic QSAR models in toxicology

被引：15

作者：

Lipnick, RL ^{[1
]}

机构：

[1] US EPA, Off Pollut Prevent & Tox, Washington, DC 20460 USA

来源：

SAR AND QSAR IN ENVIRONMENTAL RESEARCH | 1999年 / 10卷 / 2-3期

关键词：

correlative; mechanistic; QSAR; EPA; history; aquatic;

D O I：

10.1080/10629369908039178

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An outline is provided on the development and use of correlative and mechanistic approaches to predictive toxicology, with particular emphasis on the experience at the U.S. EPA as applied to assessing the potential hazard posed by new industrial chemicals for which little or no test data are provided under the Toxic Substances Control Act. This information is presented with a historical perspective.

引用

页码：239 / 248

页数：10

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