Vitamin D

被引：27

作者：

Dixon, Katie M. ^{[1
]}

Mason, Rebecca S.

机构：

[1] Univ Sydney, Dept Physiol, Sydney, NSW 2006, Australia

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | 2009年 / 41卷 / 05期

基金：

英国医学研究理事会;

关键词：

Vitamin D; 1,25-Dihydroxyvitamin D-3; Cancer; PRIMARY HUMAN KERATINOCYTES; INDUCED DNA-DAMAGE; 1-ALPHA; 25-DIHYDROXYVITAMIN D-3; 1,25-DIHYDROXYVITAMIN D-3; SKIN; CALCIUM; ANALOGS; PHOTOPROTECTION; TUMORIGENESIS; PREVENTION;

D O I：

10.1016/j.biocel.2008.06.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The primary source of vitamin D is the skin, following exposure to ultraviolet radiation. Vitamin D is well known for its effects on stimulating calcium absorption and is thus essential for maintenance of normal bone. It is also important for muscle function and has more recently been implicated in protection against several diseases including diabetes. Different pathways of action have been described for vitamin D compounds and various analogs specific to these pathways have demonstrated potential for therapeutic use. Recent studies suggest a novel role for vitamin D compounds in protection against cancer, a proposal supported by substantial epidemiological evidence. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：982 / 985

页数：4

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