Efficient solid-phase synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine antitumour antibiotics

被引：37

作者：

Kamal, A ^{[1
]}

Reddy, GSK ^{[1
]}

Reddy, KL ^{[1
]}

Raghavan, S ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(02)00188-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The solid-phase synthesis of DNA-interactive pyrrolo[2.1-c][1.4]benzodiazepine (PBD) imines and biologically important pyrrolo[2.1-c][1.4]benzodiazepine-5,11-diones on Wang resin using a reduction/cyclization procedure is reported. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2103 / 2106

页数：4

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