Oxygen transfer rate and sophorose lipid production by Candida bombicola

被引：78

作者：

Guilmanov, V

Ballistreri, A

Impallomeni, G

Gross, RA ^{[1
]}

机构：

[1] Polytech Univ, Dept Chem Chem Engn & Mat Sci, Brooklyn, NY 11201 USA

[2] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

[3] CNR, Ist Chim & Tecnol Mat Polimerici, I-95125 Catania, Italy

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 2002年 / 77卷 / 05期

关键词：

sophorose lipids; Candida bombicola; oxygen transfer rate; optimal aeration; fed-batch culture; lactonic form; acidic form;

D O I：

10.1002/bit.10177

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Sophorose lipids (SLs) have applications as surfactants and are produced at high levels by several yeasts. We developed a fed-batch shake-flask method for the production of SLs by Candida bombicola ATCC 22214. Optimal aeration, expressed in terms of oxygen transfer rate, was between 50 and 80 mM O-2/L h(-1) and resulted in maximum values for both volumetric product formation (1-1.5 g/L h(-1)) and SL yield (350 g/L). The lowest aeration levels resulted in the enrichment in saturated fatty acid SLs at the expense of unsaturated fatty acid SLs. (C) 2002 John Wiley Sons, Inc.

引用

页码：489 / 494

页数：6

共 25 条

[1]

Initial steps of sophoroselipid biosynthesis by Candida bombicola ATCC 22214 grown on glucose [J].