Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes

被引:522
作者
Nathan, D. M. [1 ]
Buse, J. B. [2 ]
Davidson, M. B. [3 ]
Ferrannini, E. [4 ]
Holman, R. R. [5 ]
Sherwin, R. [6 ,7 ]
Zinman, B. [8 ]
机构
[1] Massachusetts Gen Hosp, Ctr Diabet, Boston, MA 02114 USA
[2] Univ N Carolina, Sch Med, Chapel Hill, NC USA
[3] Charles R Drew Univ Med & Sci, Clin Ctr Res Excellence, Los Angeles, CA 90059 USA
[4] Univ Pisa, Dept Internal Med, Pisa, Italy
[5] Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Diabet Trials Unit, Oxford, England
[6] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USA
[7] Yale Univ, Sch Med, Yale Ctr Clin Invest, New Haven, CT USA
[8] Univ Toronto, Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
关键词
DIPEPTIDYL PEPTIDASE-4 INHIBITOR; INTENSIVE INSULIN THERAPY; IMPROVED GLYCEMIC CONTROL; MICROVASCULAR COMPLICATIONS; CARDIOVASCULAR EVENTS; COMBINATION THERAPY; EXENATIDE EXENDIN-4; BLOOD-GLUCOSE; DRUG-THERAPY; METFORMIN;
D O I
10.1007/s00125-008-1157-y
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The consensus algorithm for the medical management of type 2 diabetes was published in August 2006 with the expectation that it would be updated, based on the availability of new interventions and new evidence to establish their clinical role. The authors continue to endorse the principles used to develop the algorithm and its major features. We are sensitive to the risks of changing the algorithm cavalierly or too frequently, without compelling new information. An update to the consensus algorithm published in January 2008 specifically addressed safety issues surrounding the thiazolidinediones. In this revision, we focus on the new classes of medications that now have more clinical data and experience.
引用
收藏
页码:17 / 30
页数:14
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