Single blastocyst transfer: a prospective randomized trial

被引：341

作者：

Gardner, DK ^{[1
]}

Surrey, E ^{[1
]}

Minjarez, D ^{[1
]}

Leitz, A ^{[1
]}

Stevens, J ^{[1
]}

Schoolcraft, WB ^{[1
]}

机构：

[1] Colorado Ctr Reprod Med, Englewood, CO 80110 USA

来源：

FERTILITY AND STERILITY | 2004年 / 81卷 / 03期

关键词：

blastocyst; cryopreservation; culture; embryo; IVF; viability;

D O I：

10.1016/j.fertnstert.2003.07.023

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To determine the efficacy of single blastocyst transfer. Design: Prospective randomized trial. Setting: Private assisted reproductive technology unit. Patient(s): Forty-eight women undergoing IVF-embryo transfer with day 3 FSH less than or equal to 10 mIU/mL and at least 10 follicles >12 mm in diameter on day of hCG administration. Intervention(s): Embryo culture to the blastocyst stage in sequential media G1/G2 followed by transfer of either one or two blastocysts. Main Outcome Measure(s): Implantation rate, ongoing pregnancy rate, and twinning. Result(s): The transfer of a single blastocyst resulted in an implantation and ongoing pregnancy rate of 60.9% with no twins. The transfer of two blastocysts resulted in an implantation rate of 56%, an ongoing pregnancy rate of 76% with a 47.4% incidence of twins. Conclusion(s): Single blastocyst transfer is an effective method of eliminating multiple births while maintaining high pregnancy rates in this selected group of patients.

引用

页码：551 / 555

页数：5

共 28 条

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