Blood pressure control in a hypertension hospital clinic

被引:28
作者
Cuspidi, C
Lonati, L
Sampieri, L
Macca, G
Valagussa, L
Zaro, T
Michev, L
Salerno, M
Leonetti, G
Zanchetti, A
机构
[1] Univ Milan, Ctr Fisiol Clin & Ipertens, I-20122 Milan, Italy
[2] Univ Milan, Ist Clin Med Gen & Terapia Med, I-20122 Milan, Italy
[3] Osped Maggiore, IRCCS, Milan, Italy
[4] IRCCS, Osped S Lucia, Ist Auxol, Milan, Italy
关键词
anti-hypertensive treatment; blood pressure control; hypertension; left ventricular hypertrophy;
D O I
10.1097/00004872-199917060-00016
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Objectives First, to evaluate the prevalence of clinic blood pressure (BP) control (BP less than or equal to 140/90 mmHg) in a representative sample of treated hypertensive patients followed in our hypertension clinic. Second, to assess in a subgroup of these patients: (a) the proportion of BP control with both clinic blood pressure (CBP less than or equal to 140/90 mmHg) and daytime ambulatory blood pressure (ABP) (less than or equal to 132/85 mmHg) criteria, and (b) the prevalence of echocardiographic left ventricular hypertrophy (LVH) (left ventricular mass index, LVMI > 125 g/m(2) in men and > 110 g/m(2) in women). Design and methods Seven hundred consecutive hypertensive patients who attended our hypertension centre clinic during a period of 6 months and who had regularly been followed up by the same medical team were included in the study. BP was taken in the clinic by a doctor using a mercury sphygmomanometer with the participants seated. Seventy-four patients with similar demographic and clinical characteristics to the entire population of participants underwent complete echocardiographic examination and 24 h ABP monitoring. Results During follow-up, 352 of the treated patients had clinic BP less than or equal to 140/90 mmHg, 198 less than or equal to 160/95 mmHg and 150 > 160/95 mmHg, indicating that BP control was satisfactory in 50.3%, borderline in 28.3% and unsatisfactory in 21.4% of the cases. In the subgroup of 74 patients, the proportion of individuals with satisfactory clinic BP control (CBP less than or equal to 140/90 mmHg) was higher (50.0 versus 33.6%) than with satisfactory ABP control (daytime ABP values less than or equal to 132/85 mmHg). LVH was found in 21 of the 74 patients (28.3%): 12 of them had unsatisfactory CBP control and 19 had unsatisfactory ABP control. LVMI did not correlate with CBP values but only with ABP values (mean 24 h systolic r = 0.47, diastolic r = 0.40, P < 0.001; mean daytime systolic r = 0.45, mean daytime diastolic r = 0.39, P < 0.001; mean night-time systolic r = 0.38, mean night-time diastolic r = 0.38, P < 0.001). Conclusion This study demonstrates that hypertensive patients managed in a hypertension centre clinic have satisfactory CBP control in 50% of cases, but this rate seems to over-estimate the effective BP control during daily life. A large fraction of patients show persistence of LVH and this evidence of organ damage almost entirely concerns individuals with poor ABP control. J Hypertens 1999, 17:835-841 (C) Lippincott Williams & Wilkins.
引用
收藏
页码:835 / 841
页数:7
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