Reducing the risk of sexual HIV transmission - Quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use

被引：232

作者：

Varghese, B ^{[1
]}

Maher, JE ^{[1
]}

Peterman, TA ^{[1
]}

Branson, BM ^{[1
]}

Steketee, RW ^{[1
]}

机构：

[1] CDCP, Natl Ctr HIV STD & TB Prevent, Div Hiv AIDS Prevent Surveillance & Epidemiol, Atlanta, GA 30333 USA

来源：

SEXUALLY TRANSMITTED DISEASES | 2002年 / 29卷 / 01期

关键词：

D O I：

10.1097/00007435-200201000-00007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Sexual acquisition of HIV is influenced by choice of partner, sex act, and condom use. However, current risk-reduction strategies focus mainly on condom use. Goal: To estimate the contribution of choice of partner, sex act, and condom use on the per-act relative and absolute risks for HIV infection. Study Design: Per-act relative risk for HIV infection was calculated with use of estimates of HIV prevalence, risk of condom failure, HIV test accuracy, and per-act risk of HIV transmission for different sex acts. Absolute risks were calculated on the basis of these relative risk estimates. Results: Choosing a partner who tested negative instead of an untested partner reduced the relative risk of HIV infection 47-fold; using condoms, 20-fold; and choosing insertive fellatio rather than insertive anal sex, 13-fold. Choosing one risk-reduction behavior substantially reduces absolute risk of HIV infection for heterosexuals but not for men who have sex with men. Conclusion: Clarifying the magnitude of risk associated with different choices may help people make effective and sustainable changes in behavior.

引用

页码：38 / 43

页数：6

共 45 条

[1] Field evaluation of alternative testing strategies for diagnosis and differentiation of HIV-1 and HIV-2 infections in an HIV-1 and HIV-2-prevalent area [J].