Generating samples under a Wright-Fisher neutral model of genetic variation

被引：1872

作者：

Hudson, RR ^{[1
]}

机构：

[1] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

来源：

BIOINFORMATICS | 2002年 / 18卷 / 02期

关键词：

D O I：

10.1093/bioinformatics/18.2.337

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.

引用

页码：337 / 338

页数：2