Chromatin remodeling: Nucleosomes bulging at the seams

被引:58
作者
Peterson, CL [1 ]
机构
[1] Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA 01605 USA
关键词
D O I
10.1016/S0960-9822(02)00782-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ATP-dependent chromatin remodeling enzymes, such as SWI/SNF, hydrolyze thousands of ATPs to regulate gene expression on chromatin fibers. Recent mechanistic studies suggest that these enzymes generate localized changes in DNA topology that drive formation of multiple, remodeled nucleosomal states.
引用
收藏
页码:R245 / R247
页数:3
相关论文
共 17 条
  • [1] Sequence and position-dependence of the equilibrium accessibility of nucleosomal DNA target sites
    Anderson, JD
    Widom, J
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2000, 296 (04) : 979 - 987
  • [2] Roles of the histone H2A-H2B dimers and the (H3-H4)2 tetramer in nucleosome remodeling by the SWI-SNF complex
    Boyer, LA
    Shao, X
    Ebright, RH
    Peterson, CL
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (16) : 11545 - 11552
  • [3] Functional delineation of three groups of the ATP-dependent family of chromatin remodeling enzymes
    Boyer, LA
    Logie, C
    Bonte, E
    Becker, PB
    Wade, PA
    Wolffe, AP
    Wu, C
    Imbalzano, AN
    Peterson, CL
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (25) : 18864 - 18870
  • [4] Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding
    Côté, J
    Peterson, CL
    Workman, JL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) : 4947 - 4952
  • [5] Chromatin remodeling enzymes: who's on first?
    Fry, CJ
    Peterson, CL
    [J]. CURRENT BIOLOGY, 2001, 11 (05) : R185 - R197
  • [6] SWI/SNF chromatin remodeling requires changes in DNA topology
    Gavin, I
    Horn, PJ
    Peterson, CL
    [J]. MOLECULAR CELL, 2001, 7 (01) : 97 - 104
  • [7] Role of histone tails in nucleosome remodeling by Drosophila NURF
    Georgel, PT
    Tsukiyama, T
    Wu, C
    [J]. EMBO JOURNAL, 1997, 16 (15) : 4717 - 4726
  • [8] ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF
    Hamiche, A
    Sandaltzopoulos, R
    Gdula, DA
    Wu, C
    [J]. CELL, 1999, 97 (07) : 833 - 842
  • [9] Generation of superhelical torsion by ATP-dependent chromatin remodeling activities
    Havas, K
    Flaus, A
    Phelan, M
    Kingston, R
    Wade, PA
    Lilley, DMJ
    Owen-Hughes, T
    [J]. CELL, 2000, 103 (07) : 1133 - 1142
  • [10] ISWI induces nucleosome sliding on nicked DNA
    Längst, G
    Becker, PB
    [J]. MOLECULAR CELL, 2001, 8 (05) : 1085 - 1092