Inositol has behavioral effects with adaptation after chronic administration

被引：24

作者：

Cohen, H ^{[1
]}

Kotler, M ^{[1
]}

Zaplan, Z ^{[1
]}

Matar, MA ^{[1
]}

Kofman, O ^{[1
]}

Belmaker, RH ^{[1
]}

机构：

[1] BEN GURION UNIV NEGEV,FAC HLTH SCI,MINIST HLTH MENTAL HLTH CTR,BEER SHEVA,ISRAEL

来源：

JOURNAL OF NEURAL TRANSMISSION | 1997年 / 104卷 / 2-3期

关键词：

inositol; PI cycle; anxiety; animal model;

D O I：

10.1007/BF01273190

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Inositol is a simple dietary polyol that serves as a precursor in important second messenger systems. Inositol in pharmacological doses has been reported recently to be therapeutic in depression, panic disorder and obsessive compulsive disorder. We hereby report effects of inositol in the elevated plus maze model of anxiety. These results should allow development of new inositol analogs that could expand psychoactive drug development possibilities via second messenger manipulation.

引用

页码：299 / 305

页数：7

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