Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations

被引：63

作者：

Schneider, O

Michel, U

Zysk, G

Dubuis, O

Nau, R

机构：

[1] Univ Gottingen, Dept Neurol, D-3400 Gottingen, Germany

[2] Univ Dusseldorf, Dept Med Microbiol, D-4000 Dusseldorf, Germany

[3] Univ Bern, Dept Med Microbiol, CH-3012 Bern, Switzerland

来源：

NEUROLOGY | 1999年 / 53卷 / 07期

关键词：

lipoteichoic acid; teichoic acid; Streptococcus pneumoniae; meningitis; CSF;

D O I：

10.1212/WNL.53.7.1584

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Lipoteichoic and teichoic acids are components of the cell wall of Streptococcus pneumaniae. A recently developed enzyme immunoassay was used in patients with pneumococcal meningitis to investigate lipoteichoic and teichoic acid concentrations in CSF at the first lumbar puncture in relation to the clinical outcome determined by the Glasgow Outcome Scale. Lipoteichoic and teichoic acid concentrations in CSF were significantly associated with neurologic sequelae and mortality in S. pneumoniae meningitis.

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收藏

页码：1584 / 1587

页数：4

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