Preconditioning: Gender effects

被引：17

作者：

Pitcher, JM

Wang, MJ

Tsai, BM

Kher, A

Turrentine, MW

Brown, JW

Meldrum, DR

机构：

[1] Indiana Univ, Sch Med, Dept Surg, Indianapolis, IN 46202 USA

[2] Indiana Univ, Sch Med, Dept Cellular & Integrat Physiol, Indianapolis, IN USA

[3] Indiana Univ, Sch Med, Indiana Ctr Vasc Biol & Med, Indianapolis, IN USA

[4] Indiana Univ, Sch Med, Ctr Immunobiol, Indianapolis, IN USA

来源：

JOURNAL OF SURGICAL RESEARCH | 2005年 / 129卷 / 02期

关键词：

tolerance; sex; inflammation; acute injury;

D O I：

10.1016/j.jss.2005.04.015

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Preconditioning is injury induced protection from subsequent injury. During preconditioning protective cellular responses to injury are up regulated resulting in acute and delayed defense against further damage. Several studies indicate that females experience a protective advantage after acute insult compared to males. Despite evidence of gender differences in acute injury, relatively few studies have evaluated whether there are sex differences in preconditioning. Variations in patients' pre-morbid preconditioning status may explain outcome variations that are not apparent in small animal studies. This review discusses the differences in response to acute injury experienced by males and females, the basic mechanisms of preconditioning, and the sex differences in the mechanisms of preconditioning. (c) 2005 Elsevier Inc. All rights reserved.

引用

收藏

页码：202 / 220

页数：19

相关论文

共 225 条

[1] Relation between gender, etiology and survival in patients with symptomatic heart failure [J].

Adams, KF ;

Dunlap, SH ;

Sueta, CA ;

Clarke, SW ;

Patterson, JH ;

Blauwet, MB ;

Jensen, LR ;

Tomasko, L ;

Koch, G .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 28 (07) :1781-1788

[2] Early and late effects of ischemic preconditioning on microcirculation of skeletal muscle flaps [J].

Adanali, G ;

Ozer, K ;

Siemionow, M .

PLASTIC AND RECONSTRUCTIVE SURGERY, 2002, 109 (04) :1344-1351

[3] Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction [J].

Addison, PD ;

Neligan, PC ;

Ashrafpour, H ;

Khan, A ;

Zhong, AG ;

Moses, M ;

Forrest, CR ;

Pang, CY .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2003, 285 (04) :H1435-H1443

[4]

Aksöyek S, 2002, SHOCK, V18, P476

[5] Sex-specific p38 MAP kinase activation following trauma-hemorrhage:: involvement of testosterone and estradiol [J].

Angele, MK ;

Nitsch, S ;

Knöferl, MW ;

Ayala, A ;

Angele, P ;

Schildberg, FW ;

Jauch, KW ;

Chaudry, IH .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2003, 285 (01) :E189-E196

[6] Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis [J].

Angele, MK ;

Xu, YX ;

Ayala, A ;

Schwacha, MG ;

Catania, RK ;

Cioffi, WG ;

Bland, KI ;

Chaudry, IH .

SHOCK, 1999, 12 (04) :316-322

[7] Sex-based differences in clinical and angiographic outcomes after primary angioplasty or stenting for acute myocardial infraction [J].

Antoniucci, D ;

Valenti, R ;

Moschi, G ;

Migliorini, A ;

Trapani, M ;

Santoro, GM ;

Bolognese, L ;

Dovellini, EV .

AMERICAN JOURNAL OF CARDIOLOGY, 2001, 87 (03) :289-293

[8] ADENOSINE RECEPTOR SPECIFICITY IN PRECONDITIONING OF ISOLATED RABBIT CARDIOMYOCYTES - EVIDENCE OF A(3) RECEPTOR INVOLVEMENT [J].

ARMSTRONG, S ;

GANOTE, CE .

CARDIOVASCULAR RESEARCH, 1994, 28 (07) :1049-1056

[9] Gender differences in cytokine secretion by human peripheral blood mononuclear cells:: Role of estrogen in modulating LPS-induced cytokine secretion in an ex vivo septic model [J].

Asai, K ;

Hiki, N ;

Mimura, Y ;

Ogawa, T ;

Unou, K ;

Kaminishi, M .

SHOCK, 2001, 16 (05) :340-343

[10] CA2+ PRECONDITIONING ELICITS A UNIQUE PROTECTION AGAINST THE CA2+ PARADOX INJURY IN RAT-HEART - ROLE OF ADENOSINE [J].

ASHRAF, M ;

SULEIMAN, J ;

AHMAD, M .

CIRCULATION RESEARCH, 1994, 74 (02) :360-367

← 1 2 3 4 5 6 7 8 9 10 →