Self-Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

被引：1412

作者：

Blanazs, Adam ^{[1
]}

Armes, Steven P. ^{[1
]}

Ryan, Anthony J. ^{[1
]}

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2009年 / 30卷 / 4-5期

关键词：

biological applications of polymers; diblock copolymers; drug delivery systems; enzymes; self-assembly; POLYION COMPLEX VESICLES; ABC-TRIBLOCK COPOLYMER; POLYMER VESICLES; BIODEGRADABLE POLYMERSOMES; RESPONSIVE VESICLES; DIBLOCK COPOLYMER; SUPRAMOLECULAR ASSEMBLIES; RADICAL POLYMERIZATION; EMISSIVE POLYMERSOMES; MULTIPLE MORPHOLOGIES;

D O I：

10.1002/marc.200800713

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

The ability of amphiphilic block copolymers to self-assemble in selective solvents has been widely studied in academia and utilized for various commercial products. The self-assembled polymer vesicle is at the forefront of this nanotechnological revolution with seemingly endless possible uses, ranging from biomedical to nanometer-scale enzymatic reactors. This review is focused on the inherent advantages in using polymer vesicles over their small molecule lipid counterparts and the potential applications in biology for both drug delivery and synthetic cellular reactors.

引用

页码：267 / 277

页数：11

共 148 条

[1]

Effect of block length, polydispersity, and salt concentration on PEO-PDEAMA block copolymer structures in dilute solution [J].