Synthesis of oxazolinyl aziridines

被引：31

作者：

Florio, S

Troisi, L

Capriati, V

Ingrosso, G

机构：

[1] Univ Bari, CNR, Ctr Studio Metodol Innovat Sintesi Organ, Dipartimento Farmacochim, I-70125 Bari, Italy

[2] Univ Lecce, Dipartimento Biol, I-73100 Lecce, Italy

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

关键词：

lithiation; aziridinyllithiums; oxazolinyl aziridines;

D O I：

10.1016/S0040-4039(99)01212-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aziridinyllithiums 4a and 4b, which are stable at low temperature, can be generated by deprotonation of 3a and 3b. Oxazolinyl aziridines 5a-j and 6a-b have been prepared by the reaction of oxazolinyl aziridinyllithiums 4a and 4b with electrophiles. Aziridines 6c and 6d were, instead, synthesized by a Darzens-like reaction from 2-(1-chloroethyl)-2-oxazoline 1b. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：6101 / 6104

页数：4

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