Identification of steviol glucuronide in human urine

被引：79

作者：

Geuns, JMC

Buyse, J

Vankeirsbilck, A

Temme, EHM

Compernolle, F

Toppet, S

机构：

[1] Katholieke Univ Leuven, Lab Funct Biol, B-3001 Louvain, Belgium

[2] Fac Appl Biosci & Engn, Lab Physiol & Immunl Domest Anim, B-3001 Louvain, Belgium

[3] Fac Med, Dept Publ Hlth, Div Nutr Epidemiol, B-3000 Louvain, Belgium

[4] Katholieke Univ Leuven, Lab Organ Synthesis, B-3001 Louvain, Belgium

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2006年 / 54卷 / 07期

关键词：

Stevia rebaudiana (Bertoni) Bertoni (Asteraceae); stevioside degradation; steviol; steviol glucuronide;

D O I：

10.1021/jf052693e

中图分类号：

S [农业科学];

学科分类号：

09 [农学];

摘要：

Stevioside (250 mg capsules) was given three times daily to 10 healthy subjects. Steviol glucuronide (steviol 19-O-beta-D-glucopyranosiduronic acid; MM, 494.58; melting point, 198-199 degrees C) was characterized in the 24 h urine as the only excretion product of oral stevioside by MS, NMR, IR, and UV spectroscopy. This is the first report on the unambiguous identification of steviol glucuronide in human urine.

引用

页码：2794 / 2798

页数：5

共 15 条

[1]

Buyse J.G, 2004, P 1 S SAF STEV, P51

[2]

Metabolism of stevioside and rebaudioside A from Stevia rebaudiana extracts by human microflora [J].