Oxazolidinones: New antibacterial agents

被引:57
作者
Ford, CW
Hamel, JC
Stapert, D
Moerman, JK
Hutchinson, DK
Barbachyn, MR
Zurenko, GE
机构
[1] Pharmacia and Upjohn Inc., Kalamazoo, MI 49001
关键词
D O I
10.1016/S0966-842X(97)01032-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The oxazolidinones are a new chemical class of synthetic antibacterial agents that are active orally or intravenously against multidrug-resistant Gram-positive bacteria. Their unique mechanism of action and activity against bacteria that pose therapeutic problems in hospital and community treatments make them promising candidates for antimicrobial agents.
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页码:196 / 200
页数:5
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