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Effects of Panax ginseng in Neurodegenerative Diseases

被引：178
作者：
Cho, Ik-Hyun [1 ,2 ]
机构：
[1] Kyung Hee Univ, Coll Oriental Med, Dept Anat, Seoul 130701, South Korea
[2] Kyung Hee Univ, Inst Oriental Med, Seoul 130701, South Korea
来源：
JOURNAL OF GINSENG RESEARCH | 2012年 / 36卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
Panax ginseng; Ginsenosides; Neuroprotection; Neurodegeneration; MULTIPLE-SCLEROSIS; PC12; CELLS; ANTIINFLAMMATORY MECHANISM; MICROGLIAL ACTIVATION; ACIDIC POLYSACCHARIDE; COGNITIVE PERFORMANCE; INDUCED NEUROTOXICITY; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; INDUCED APOPTOSIS;
D O I：
10.5142/jgr.2012.36.4.342
中图分类号：
Q94 [植物学];
学科分类号：
071001 [植物学];
摘要：
Ginseng, the root of the Panax ginseng, has been a popular and widely-used traditional herbal medicine in Korea, China, and Japan for thousands of years. Now it has become popular as a functional health food and is used globally as a natural medicine. Evidence is accumulating in the literature on the physiological and pharmacological effects of P ginseng on neurodegenerative diseases. Possible ginseng- or ginsenosides-mediated neuroprotective mechanisms mainly involve maintaining homeostasis, and anti-inflammatory, anti-oxidant, anti-apoptotic, and immune-stimulatory activities. This review considers publications dealing with the various actions of P ginseng that are indicative of possible neurotherapeutic efficacies in neurodegenerative diseases and neurological disorders such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and amyotrophic lateral sclerosis and multiple sclerosis.
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收藏
页码：342 / 353
页数：12
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