Genetic Instability, DNA Damage and Atherosclerosis

被引：14

作者：

Andreassi, Maria Grazia ^{[1
]}

Botto, Nicoletta ^{[1
]}

机构：

[1] G Pasquinucci Hosp, CNR, Inst Clin Physiol, Lab Cellular Biol, I-54100 Massa, Italy

来源：

CELL CYCLE | 2003年 / 2卷 / 03期

关键词：

Atherosclerosis; Cancer; Mutation; DNA damage; Chemopreventive therapeutic agents;

D O I：

10.4161/cc.2.3.403

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

We review the role of somatic mutations and genetic instability in the pathogenesis of atherosclerosis, suggesting novel therapeutic approaches.

引用

页码：224 / 227

页数：4

共 51 条

[1]

Andreassi MG, 2000, ENVIRON MOL MUTAGEN, V35, P265, DOI 10.1002/1098-2280(2000)35:4<265::AID-EM1>3.0.CO

[2]

2-M

[3]

Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease [J].

Andreassi, MG ;

Botto, N ;

Cocci, F ;

Battaglia, D ;

Antonioli, E ;

Masetti, S ;

Manfredi, S ;

Colombo, MG ;

Biagini, A ;

Clerico, A .

HUMAN GENETICS, 2003, 112 (02) :171-177

[4]

Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage [J].

Andreassi, MG .

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2003, 543 (01) :67-86

[5]

Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty [J].

Andreassi, MG ;

Botto, N ;

Rizza, A ;

Colombo, MG ;

Palmieri, C ;

Berti, S ;

Manfredi, S ;

Masetti, S ;

Clerico, A ;

Biagini, A .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 40 (05) :862-868

[6]

Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells - Potential role of p53 in regulation of vascular smooth muscle cell growth [J].

Aoki, M ;

Morishita, R ;

Matsushita, H ;

Hayashi, S ;

Nakagami, H ;

Yamamoto, K ;

Moriguchi, A ;

Kaneda, Y ;

Higaki, J ;

Ogihara, T .

HYPERTENSION, 1999, 34 (02) :192-200

[7]

Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement [J].

Bailey, LB ;

Gregory, JF .

JOURNAL OF NUTRITION, 1999, 129 (05) :919-922

[8]

Pathophysiological effects of radiation on atherosclerosis development and progression, and the incidence of cardiovascular complications [J].

Basavaraju, SR ;

Easterly, CE .

MEDICAL PHYSICS, 2002, 29 (10) :2391-2403

[9]

Atherosclerotic risks from chemicals: Part I. Toxicological observations and mechanisms of atherosclerosis [J].

Basavaraju, SR ;

Jones, TD .

ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1998, 35 (01) :152-164

[10]

EVIDENCE FOR A MONOCLONAL ORIGIN OF HUMAN ATHEROSCLEROTIC PLAQUES [J].

BENDITT, EP ;

BENDITT, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (06) :1753-1756

← 1 2 3 4 5 6 →