Effects of verapamil and CSL antivenom on Chironex fleckeri (Box-jellyfish) induced mortality

被引:14
作者
Bloom, DA
Burnett, JW
Hebel, JR
Alderslade, P
机构
[1] Univ Maryland, Sch Med, Dept Dermatol, Baltimore, MD 21201 USA
[2] Univ Maryland, Grad Program Marine Estuarine Environm Sci, Baltimore, MD 21201 USA
[3] Univ Maryland, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA
[4] No Terr Museum Arts & Sci, Darwin, NT, Australia
关键词
D O I
10.1016/S0041-0101(98)00245-1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Ovine antivenom prolonged survival in mice challenged with intravenous Chironex fleckeri venom over a limited dose range. Verapamil enhanced the beneficial effect of ovine antivenom. This data suggests that there may be an, as yet undefined, optimal antivenom dose for humans and that verapamil, used in combination with antivenom is an effective agent. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1621 / 1626
页数:6
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