Pharmaceutical Aspects of Drug Eluting Stents

被引：27

作者：

Deconinck, E. ^{[1
,2
]}

Sohier, I. ^{[2
]}

De Scheerder, I. ^{[2
]}

Van Den Mooter, G. ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Lab Pharmaceut Technol & Biopharm, B-3000 Louvain, Belgium

[2] Ziscoat NV, B-3001 Heverlee, Belgium

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 2008年 / 97卷 / 12期

关键词：

cardiovascular diseases; drug eluting stents; controlled release;

D O I：

10.1002/jps.21356

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

This review focuses on the pharmaceutical aspects of the development of drug eluting stents. It discusses the different processes that can be used to obtain a controlled release of a drug from the stent as well as the coatings therefore applied. Results obtained for stents already available on the market or in a far stage of development are discussed. In a final part possible future research areas as well as expected new evolutions in the design of drug eluting stents are presented. (c) 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97:5047-5060, 2008

引用

页码：5047 / 5060

页数：14

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