In vitro activities of polycationic peptides alone and in combination with clinically used antimicrobial agents against Rhodococcus equi

被引:14
作者
Giacometti, A [1 ]
Cirioni, O [1 ]
Ancarani, F [1 ]
Del Prete, MS [1 ]
Fortuna, M [1 ]
Scalise, G [1 ]
机构
[1] Univ Ancona, Inst Infect Dis & Publ Hlth, Ancona, Italy
关键词
D O I
10.1128/AAC.43.8.2093
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The in vitro activities of magainin II, nisin, and ranalexin alone and in combination with other antimicrobial agents against six clinical isolates of Rhodococcus equi were investigated by MIC and time-kill studies. All isolates were more susceptible to nisin. A positive interaction was observed when the peptides were combined with ampicillin, ceftriaxone, rifabutin, rifampin, azithromycin, clarithromycin, and vancomycin.
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收藏
页码:2093 / 2096
页数:4
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