A prospective study on oocyte survival rate after ICSI: Influence of injection technique and morphological features

被引：71

作者：

Ebner, T ^{[1
]}

Yaman, C ^{[1
]}

Moser, M ^{[1
]}

Sommergruber, M ^{[1
]}

Jesacher, K ^{[1
]}

Tews, G ^{[1
]}

机构：

[1] Womens Gen Hosp, IVF Unit, A-4010 Linz, Austria

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2001年 / 18卷 / 12期

关键词：

degeneration of oocytes; fertilization rate; ICSI technique; morphology of oocyte;

D O I：

10.1023/A:1013171505702

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose. To determine the influence of technical pitfalls and oocyte morphology on survival rate and cleavage behavior after ICSI. Methods. A total of 2210 injection procedures was examined for morphological and technical deviations. Survival rate and cleavage behavior were evaluated. Results. In 77.8% of all cases ICSI was unsuspicous. Out of 491 deviations from optimal injection deep penetration of the oocyte and abundant presence of cumulus cells showed significant correlation with degeneration rate (p < 0.001). Morphological anomalies associated with the periphery of the oocyte were rather related to degeneration than cytoplasmic anomalies (p < 0.001). Early embryonic development was not impaired by technical or morphological parameters. Conclusions: To conclude, these prospective data may be of prognostic value in regard of the number of embryos available for transfer and may help to improve treatment outcome.

引用

页码：623 / 628

页数：6

共 27 条

[1] Intracytoplasmic sperm injection in dysmorphic human oocytes [J].