Polycytella hominis is a mutated form of Scedosporium apiospermum

被引：27

作者：

Borman, AM

Campbell, CK

Linton, CJ

Bridge, PD

Johnson, EM

机构：

[1] Hlth Protect Agcy, Mycol Reference Lab, SW Reg Lab, Bristol BS2 8EL, Avon, England

[2] British Antarctic Survey, Cambridge CB3 0ET, England

来源：

MEDICAL MYCOLOGY | 2006年 / 44卷 / 01期

基金：

英国自然环境研究理事会;

关键词：

Scedosporium; Pseudallescheria; Polycytella; mycetoma; rDNA sequence;

D O I：

10.1080/13693780500179678

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

PCR amplification and sequencing of two separate regions of the nuclear ribosomal repeat region revealed that Polycytella hominis, a hyphomycete isolated from a human case of mycetoma, was genetically indistinguishable from Scedosporium apiospermum (the anamorph of Pseudallescheria boydii). These organisms also exhibited remarkably similar susceptibility profiles to common antifungal agents. P. hominis is thus likely to be a mutant of S. apiospermum showing abnormalities of sporulation, for which a possible mechanism is discussed. Polycytella hominis should thus be regarded as a synonym of Scedosporium apiospermum.

引用

页码：33 / 39

页数：7

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[1] BASIC LOCAL ALIGNMENT SEARCH TOOL [J].