Neurobiology of gambling behaviors

被引：75

作者：

Potenza, Marc N. ^{[1
,2
,3
]}

机构：

[1] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT USA

[3] Yale Univ, Sch Med, Ctr Child Study, New Haven, CT 06510 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2013年 / 23卷 / 04期

关键词：

IMPULSE CONTROL DISORDERS; PATHOLOGICAL GAMBLERS; PSYCHIATRIC-DISORDERS; PARKINSONS-DISEASE; DOPAMINE RELEASE; HEALTHY CONTROLS; DECISION-MAKING; REWARD; TASK; ADDICTIONS;

D O I：

10.1016/j.conb.2013.03.004

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

For many, gambling is a recreational activity that is performed periodically without ill effects, but for some, gambling may interfere with life functioning. A diagnostic entity, pathological gambling (PG), is currently used to define a condition marked by excessive and problematic gambling. In this review, the current status of understanding of the neurobiologies of gambling and PG is described. Multiple neurotransmitter systems (norepinephrine, serotonin, dopamine, opioid and glutamate) and brain regions (ventral striatum, ventromedial prefrontal cortex, insula, among others) have been implicated in gambling and PG. Considerations for future directions in gambling research, with a view towards translating neurobiological advances into more effective prevention and treatment strategies, are discussed.

引用

页码：660 / 667

页数：8

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