Prevalence of coeliac disease in Turner syndrome

被引：50

作者：

Ivarsson, SA ^{[1
]}

Carlsson, A

Bredberg, A

Alm, J

Aronsson, S

Gustafsson, J

Hagenäs, L

Häger, A

Kriström, B

Marcus, C

Moëll, C

Nilsson, KO

Tuvemo, T

Westphal, O

Albertsson-Wikland, K

Aman, J

机构：

[1] Univ Lund, Dept Paediat, Malmo Univ Hosp, S-20502 Malmo, Sweden

[2] Univ Lund, Dept Bacteriol, Malmo Univ Hosp, S-20502 Malmo, Sweden

[3] Univ Gothenburg, Dept Paediat, Gothenburg, Sweden

[4] Linkoping Univ, Dept Paediat, Linkoping, Sweden

[5] Umea Univ, Dept Paediat, Umea, Sweden

[6] Uppsala Univ, Dept Paediat, Uppsala, Sweden

[7] Karolinska Hosp, Dept Paediat, S-10401 Stockholm, Sweden

[8] Huddinge Hosp, Stockholm, Sweden

[9] Cent Hosp, Halmstad, Sweden

[10] Cent Hosp, Orebro, Sweden

来源：

ACTA PAEDIATRICA | 1999年 / 88卷 / 09期

关键词：

coeliac disease; IgA-antiendomysium antibodies; IgA-antigliadin antibodies; Turner syndrome;

D O I：

10.1080/08035259950168397

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This study was undertaken to investigate the prevalence of coeliac disease in children and adolescents with Turner syndrome. Eighty-seven children and adolescents with Turner syndrome were screened for IgA-antiendomysium antibodies (EMA) and IgA-antigliadin antibodies (AGA), 5% (4/87) being found to be EMA-positive, and 15% (13/87) to have AGA levels above normal. Of the 10 patients who were either AGA- or EMA-positive and further investigated with intestinal biopsy, four manifested villous atrophy (i.e. all three of the EMA-positive patients, but only one of the seven AGA-positive patients). The results suggest EMA-positivity to be a good immunological marker for use in screening for coeliac disease, and such screening to be justified in patients with Turner syndrome.

引用

页码：933 / 936

页数：4

共 27 条

[1] Value of serologic markers for clinical diagnosis and population studies of coeliac disease [J].

Ascher, H ;

HahnZoric, M ;

Hanson, LA ;

Kilander, AF ;

Nilsson, LA ;

Tlaskalova, H .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1996, 31 (01) :61-67

[2] Celiac disease and Turner syndrome [J].

Bonamico, M ;

Bottaro, G ;

Pasquino, AM ;

Caruso-Nicoletti, M ;

Mariani, P ;

Gemme, G ;

Paradiso, E ;

Ragusa, MC ;

Spina, M .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1998, 26 (05) :496-499

[3] ANTIGLIADIN AND ANTIENDOMYSIUM ANTIBODY DETERMINATION FOR CELIAC-DISEASE [J].

BURGINWOLFF, A ;

GAZE, H ;

HADZISELIMOVIC, F ;

HUBER, H ;

LENTZE, MJ ;

NUSSLE, D ;

REYMONDBERTHET, C .

ARCHIVES OF DISEASE IN CHILDHOOD, 1991, 66 (08) :941-947

[4] Prevalence of IgA-antigliadin antibodies and IgA-antiendomysium antibodies related to celiac disease in children with Down syndrome [J].

Carlsson, A ;

Axelsson, I ;

Borulf, S ;

Bredberg, A ;

Forslund, M ;

Lindberg, B ;

Sjöberg, K ;

Ivarsson, SA .

PEDIATRICS, 1998, 101 (02) :272-275

[5] DOWNS-SYNDROME AND CELIAC-DISEASE - THE PREVALENCE OF HIGH IGA-ANTIGLIADIN ANTIBODIES AND HLA-DR AND DQ ANTIGENS IN TRISOMY-21 [J].

CASTRO, M ;

CRINO, A ;

PAPADATOU, B ;

PURPURA, M ;

GIANNOTTI, A ;

FERRETTI, F ;

COLISTRO, F ;

MOTTOLA, L ;

DIGILIO, MC ;

LUCIDI, V ;

BORRELLI, P .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1993, 16 (03) :265-268

[6] INCREASING INCIDENCE OF CHILDHOOD CELIAC-DISEASE IN SWEDEN - RESULTS OF A NATIONAL STUDY [J].

CAVELL, B ;

STENHAMMAR, L ;

ASCHER, H ;

DANIELSSON, L ;

DANNAEUS, A ;

LINDBERG, T ;

LINDQUIST, B .

ACTA PAEDIATRICA, 1992, 81 (08) :589-592

[7]

CORRAO G, 1995, GASTROENTEROLOGY, V108, P608

[8]

DeVitis I, 1996, ACTA PAEDIATR, V85, P56

[9] Screening for coeliac disease in apparently healthy blood donors [J].

Grodzinsky, E .

ACTA PAEDIATRICA, 1996, 85 :36-38

[10] ANTI-ENDOMYSIUM AND ANTIGLIADIN ANTIBODIES AS SEROLOGICAL MARKERS FOR CELIAC-DISEASE IN CHILDHOOD - A CLINICAL-STUDY TO DEVELOP A PRACTICAL ROUTINE [J].

GRODZINSKY, E ;

JANSSON, G ;

SKOGH, T ;

STENHAMMAR, L ;

FALTHMAGNUSSON, K .

ACTA PAEDIATRICA, 1995, 84 (03) :294-298

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