Hippocampus in health and disease: An overview

被引:392
作者
Anand, Kuljeet Singh [1 ]
Dhikav, Vikas [1 ]
机构
[1] PGIMER Guru Gobind Singh Indraprasth Univ, Dept Neurol, New Delhi, India
关键词
AD; atrophy; drug target; early Alzheimers; hippocampus; hippocampal atrophy; prevention; TEMPORAL-LOBE EPILEPSY; COGNITIVE IMPAIRMENT; SYNAPTIC PLASTICITY; ADULT NEUROGENESIS; ALZHEIMERS-DISEASE; DENTATE GYRUS; STRESS; ATROPHY; MEMORY; GLUCOCORTICOIDS;
D O I
10.4103/0972-2327.104323
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders. In last decade or so, lot has been learnt about conditions that affect hippocampus and produce changes ranging from molecules to morphology. Progresses in radiological delineation, electrophysiology, and histochemical characterization have made it possible to study this archicerebral structure in greater detail. Present paper attempts to give an overview of hippocampus, both in health and diseases.
引用
收藏
页码:239 / 246
页数:8
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