Newborn primary congenital glaucoma: Histopathologic features of the anterior chamber filtration angle

被引:22
作者
Perry, Lynn P. [2 ]
Jakobiec, Frederick A. [1 ,2 ]
Zakka, Fouad R. [2 ]
Walton, David S. [2 ]
机构
[1] Harvard Univ, Massachusetts Eye & Ear Infirm, Sch Med, David G Cogan Lab Ophthalm Pathol, Boston, MA 02114 USA
[2] Harvard Univ, Dept Ophthalmol, Sch Med, Boston, MA 02114 USA
来源
JOURNAL OF AAPOS | 2012年 / 16卷 / 06期
关键词
UPDATE;
D O I
10.1016/j.jaapos.2012.06.012
中图分类号
R77 [眼科学];
学科分类号
100212 [眼科学];
摘要
We present histopathologic findings that have not been previously reported as associated with abnormalities of the anterior chamber angle underlying newborn primary congenital glaucoma as a distinct entity. The major histopathologic findings were partial absence and retrodisplacement of Schlemm's canal, hypoplasia of the trabecular meshwork, broad attachment of ciliary muscle to the meshwork, and anterior insertion of hypoplastic iris with the formation of a pseudomembrane. These profound anatomic derangements explain why goniosurgery is frequently unsuccessful in cases of newborn glaucoma.
引用
收藏
页码:565 / 568
页数:4
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