Can boron get bacteria talking?

被引:22
作者
Coulthurst, SJ [1 ]
Whitehead, NA [1 ]
Welch, M [1 ]
Salmond, GPC [1 ]
机构
[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England
关键词
D O I
10.1016/S0968-0004(02)02096-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A structure for the bacterial signal 'Autoinducer-2' has been determined by an unusual route. Unexpectedly, this molecule was found to contain boron, raising many questions about Autoinducer-2 and its possible role in bacterial communication.
引用
收藏
页码:217 / 219
页数:3
相关论文
共 17 条
[1]   MULTIPLE SIGNALING SYSTEMS CONTROLLING EXPRESSION OF LUMINESCENCE IN VIBRIO-HARVEYI - SEQUENCE AND FUNCTION OF GENES ENCODING A 2ND SENSORY PATHWAY [J].
BASSLER, BL ;
WRIGHT, M ;
SILVERMAN, MR .
MOLECULAR MICROBIOLOGY, 1994, 13 (02) :273-286
[2]   Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi [J].
Bassler, BL ;
Greenberg, EP ;
Stevens, AM .
JOURNAL OF BACTERIOLOGY, 1997, 179 (12) :4043-4045
[3]   Structural identification of a bacterial quorum-sensing signal containing boron [J].
Chen, X ;
Schauder, S ;
Potier, N ;
Van Dorsselaer, A ;
Pelczer, I ;
Bassler, BL ;
Hughson, FM .
NATURE, 2002, 415 (6871) :545-549
[4]   Signaling system in Porphyromonas gingivalis based on a LuxS protein [J].
Chung, WSO ;
Park, Y ;
Lamont, RJ ;
McNab, R ;
Barbieri, B ;
Demuth, DR .
JOURNAL OF BACTERIOLOGY, 2001, 183 (13) :3903-3909
[5]   Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS [J].
Fong, KP ;
Chung, WSO ;
Lamont, RJ ;
Demuth, DR .
INFECTION AND IMMUNITY, 2001, 69 (12) :7625-7634
[6]   Evidence for a signaling system in Helicobacter pylori:: detection of a luxS-Encoded autoinducer [J].
Joyce, EA ;
Bassler, BL ;
Wright, A .
JOURNAL OF BACTERIOLOGY, 2000, 182 (13) :3638-3643
[7]   The ins and outs of peptide signaling [J].
Lazazzera, BA ;
Grossman, AD .
TRENDS IN MICROBIOLOGY, 1998, 6 (07) :288-294
[8]   Regulation of quorum sensing in Vibrio harveyi by LuxO and Sigma-54 [J].
Lilley, BN ;
Bassler, BL .
MOLECULAR MICROBIOLOGY, 2000, 36 (04) :940-954
[9]   Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes [J].
Lyon, WR ;
Madden, JC ;
Levin, JC ;
Stein, JL ;
Caparon, MG .
MOLECULAR MICROBIOLOGY, 2001, 42 (01) :145-157
[10]   Requirement of borate cross-linking of cell wall rhamnogalacturonan II for Arabidopsis growth [J].
O'Neill, MA ;
Eberhard, S ;
Albersheim, P ;
Darvill, AG .
SCIENCE, 2001, 294 (5543) :846-849