Transcriptional regulation of secondary metabolite biosynthesis in plants

被引：255

作者：

Patra, Barunava ^{[1
]}

Schluttenhofer, Craig ^{[1
]}

Wu, Yongmei ^{[1
]}

Pattanaik, Sitakanta ^{[1
]}

Yuan, Ling ^{[1
]}

机构：

[1] Univ Kentucky, Dept Plant & Soil Sci, Kentucky Tobacco Res & Dev Ctr, Lexington, KY 40546 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS | 2013年 / 1829卷 / 11期

关键词：

Transcriptional regulation; Flavonoids; Terpenoid indole alkaloids; Terpenes; HELIX-LOOP-HELIX; INDOLE ALKALOID BIOSYNTHESIS; CATHARANTHUS-ROSEUS; ANTHOCYANIN BIOSYNTHESIS; FLAVONOID BIOSYNTHESIS; FUNCTIONAL-ANALYSIS; NICOTINE BIOSYNTHESIS; INDUCED EXPRESSION; ARTEMISIA-ANNUA; SYNTHASE GENE;

D O I：

10.1016/j.bbagrm.2013.09.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Plants produce thousands of secondary metabolites (a.k.a. specialized metabolites) of diverse chemical nature. These compounds play important roles in protecting plants under adverse conditions. Many secondary metabolites are valued for their pharmaceutical properties. Because of their beneficial effects to health, biosynthesis of secondary metabolites has been a prime focus of research. Many transcription factors have been characterized for their roles in regulating biosynthetic pathways at the transcriptional level. The emerging picture of transcriptional regulation of secondary metabolite biosynthesis suggests that the expression of activators and repressors, in response to phytohormones and different environmental signals, forms a dynamic regulatory network that fine-tune the timing, amplitude and tissue specific expression of pathway genes and the subsequent accumulation of these compounds. Recent research has revealed that some metabolic pathways are also controlled by posttranscriptional and posttranslational mechanisms. This review will use recent developments in the biosynthesis of flavonoids, alkaloids and terpenoids to highlight the complexity of transcriptional regulation of secondary metabolite biosynthesis. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：1236 / 1247

页数：12

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