The many-roles of CD40 in cell-mediated inflammatory responses

被引：256

作者：

Stout, RD ^{[1
]}

Suttles, J ^{[1
]}

机构：

[1] E TENNESSEE STATE UNIV, QUILLEN DISHNER COLL MED, DEPT BIOCHEM, PROGRAM IMMUNOL, JOHNSON CITY, TN 37614 USA

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 10期

关键词：

D O I：

10.1016/0167-5699(96)10060-I

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In addition to B cells, CD40 is expressed by a variety of cells including dendritic cells, monocytes, fibroblasts and vascular endothelial cells. As discussed here by Robert Stout and Jill Suttles, CD40-CD40 ligand interactions can influence many aspects of T-cell-mediated inflammatory response, such as cell extravasation, production of inflammatory and chemotactic cytokines, as well as activation of macrophage effector functions.

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页码：487 / 492

页数：6

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