Trehalose-based octopus glycosides for the synthesis of carbohydrate-centered PAMAM dedrimers and thiourea-bridged glycoclusters

被引:49
作者
Dubber, M [1 ]
Lindhorst, TK [1 ]
机构
[1] Univ Kiel, Inst Organ Chem, D-24098 Kiel, Germany
关键词
D O I
10.1021/ol016717o
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] The nonreducing disaccharide trehalose was modified into an octa-amino-functionalized core molecule to serve in the synthesis of carbohydrate-centered PAMAM glycodendrimers and thiourea-bridged glycoclusters.
引用
收藏
页码:4019 / 4022
页数:4
相关论文
共 46 条
[1]   TERTIARY PHOSPHANE-TETRACHLOROMETHANE, A VERSATILE REAGENT FOR CHLORINATION, DEHYDRATION, AND P-N LINKAGE [J].
APPEL, R .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1975, 14 (12) :801-811
[2]  
Appel R., 1975, Angew. Chem, V87, P863
[3]   Synthesis and biological evaluation of α-D-mannopyranoside-containing dendrimers [J].
Ashton, PR ;
Hounsell, EF ;
Jayaraman, N ;
Nilsen, TM ;
Spencer, N ;
Stoddart, JF ;
Young, M .
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (10) :3429-3437
[4]   Chemical glycobiology [J].
Bertozzi, CR ;
Kiessling, LL .
SCIENCE, 2001, 291 (5512) :2357-2364
[5]  
De Brabander-van den Berg E.M.M., 1993, ANGEW CHEM INT EDIT, V105, P1370
[6]   Enzymatic synthesis of disaccharides by β-galactosidase-catalyzed glycosylation of a glycocluster [J].
de Santiago, R ;
Fernández-Mayoralas, A ;
García-Junceda, E .
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2000, 11 (2-3) :71-79
[7]   POLY(PROPYLENE IMINE) DENDRIMERS - LARGE-SCALE SYNTHESIS BY HETEREOGENEOUSLY CATALYZED HYDROGENATIONS [J].
DEBRABANDERVANDENBERG, EMM ;
MEIJER, EW .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (09) :1308-1311
[8]   Synthesis of octopus glycosides: core molecules for the construction of glycoclusters and carbohydrate-centered dendrimers [J].
Dubber, M ;
Lindhorst, TK .
CARBOHYDRATE RESEARCH, 1998, 310 (1-2) :35-41
[9]   Synthesis of chiral carbohydrate-centered dendrimers [J].
Dubber, M ;
Lindhorst, TK .
CHEMICAL COMMUNICATIONS, 1998, (12) :1265-1266
[10]   Synthesis of carbohydrate-centered oligosaccharide mimetics equipped with a functionalized tether [J].
Dubber, M ;
Lindhorst, TK .
JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (17) :5275-5281