Assessment of subchondral bone blood flow in the rabbit femoral condyle using the laser speckle method

被引:5
作者
Fukuoka, S
Hotokebuchi, T
Terada, K
Kobara, N
Fujii, H
Sugioka, Y
Iwamoto, Y
机构
[1] Kyushu Univ, Dept Orthopaed Surg, Fac Med, Higashi Ku, Fukuoka 812, Japan
[2] Kyushu Inst Technol, Dept Comp Sci & Elect, Iizuka, Fukuoka 820, Japan
基金
美国国家科学基金会;
关键词
D O I
10.1002/jor.1100170311
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The laser speckle method is a new form of flowmetry that can obtain a two-dimensional distribution of blood flow in tissue. This method is a noncontact, simple, and rapid technique that may aid in the diagnosis of osteonecrosis. We investigated whether the subchondral bone blood now within the femoral condyles of rabbits could be measured by the laser speckle method. The hydrogen washout method was chosen as a comparison technique because of its ability to allow repetitive measurements of blood flow in various conditions in one rabbit and because of its reliability, which already has been established. We simultaneously measured the bone blood flow in 20 femoral condyles of 10 rabbits with the laser speckle and hydrogen washout methods and found a significant correlation between the blood now levels with use of these two methods. For the clinical application of the laser speckle method, we also investigated the influence of cartilage thickness on the measurements and the depth in the bone to which blood flow could be measured with this method. A cartilage thickness of 0.2 mm did not influence the measurement of the bone blood flow, and the depth in the bone to which the laser speckle method could be used was: approximately 2 mm.
引用
收藏
页码:368 / 375
页数:8
相关论文
共 24 条
[1]   Effect of long-term topical betaxolol on tissue circulation in the iris and optic nerve head [J].
Araie, M ;
Muta, K .
EXPERIMENTAL EYE RESEARCH, 1997, 64 (02) :167-172
[2]   FLOW VISUALIZATION BY MEANS OF SINGLE-EXPOSURE SPECKLE PHOTOGRAPHY [J].
FERCHER, AF ;
BRIERS, JD .
OPTICS COMMUNICATIONS, 1981, 37 (05) :326-330
[3]   EVALUATION OF BLOOD-FLOW BY LASER SPECKLE IMAGE SENSING .1. [J].
FUJII, H ;
NOHIRA, K ;
YAMAMOTO, Y ;
IKAWA, H ;
OHURA, T .
APPLIED OPTICS, 1987, 26 (24) :5321-5325
[4]   VISUALIZATION OF RETINAL BLOOD-FLOW BY LASER SPECKLE FLOWGRAPHY [J].
FUJII, H .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 1994, 32 (03) :302-304
[5]   LASER DOPPLER FLOWMETRY AND BONE BLOOD-FLOW IN AN ISOLATED PERFUSED PREPARATION [J].
HANDLEY, RC ;
ESSEX, T ;
POOLEY, J .
JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY, 1990, 14 (05) :201-204
[6]   MEASUREMENT OF MICROVASCULAR BLOOD-FLOW IN CANCELLOUS BONE USING LASER DOPPLER FLOWMETRY AND XE-133-CLEARANCE [J].
HELLEM, S ;
JACOBSSON, LS ;
NILSSON, GE ;
LEWIS, DH .
INTERNATIONAL JOURNAL OF ORAL SURGERY, 1983, 12 (03) :165-177
[7]   LASER-DOPPLER FLOWMETRY FOR ESTIMATION OF BONE BLOOD-FLOW - STUDIES OF REPRODUCIBILITY AND CORRELATION WITH MICROSPHERE TECHNIQUE [J].
LAUSTEN, GS ;
KIAER, T ;
DAHL, B .
JOURNAL OF ORTHOPAEDIC RESEARCH, 1993, 11 (04) :573-580
[8]   Haemodynamic changes in early phase reflex sympathetic dystrophy [J].
Matsumura, H ;
Jimbo, Y ;
Watanabe, K .
SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY, 1996, 30 (02) :133-138
[9]   ACUTE EFFECT OF TRACTION, COMPRESSION, AND HIP-JOINT TAMPONADE ON BLOOD-FLOW OF THE FEMORAL-HEAD - AN EXPERIMENTAL-MODEL [J].
NAITO, M ;
SCHOENECKER, PL ;
OWEN, JH ;
SUGIOKA, Y .
JOURNAL OF ORTHOPAEDIC RESEARCH, 1992, 10 (06) :800-806
[10]  
NIV AI, 1980, T ORTHOP RES SOC, V5, P156