Transforming growth factor β in infectious disease:: always there for the host and the pathogen

被引：28

作者：

Fitzpatrick, DR

Bielefeldt-Ohmann, H

机构：

[1] Queensland Inst Med Res, Leukocyte Biol Unit, Brisbane, Qld 4029, Australia

[2] Univ Queensland, Dept Microbiol, St Lucia, Qld 4072, Australia

来源：

TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 06期

关键词：

D O I：

10.1016/S0966-842X(99)01498-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

At the portals of pathogen entry, there are pools of the latent form of a potent cytokine, transforming growth factor beta (TGF-beta). Many infections activate these pools and stimulate further TGF-beta expression. As well as potent immunomodulation, activated TGF-beta might have important effects on pathogen entry, replication, persistence, latency and oncogenesis.

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页码：232 / 236

页数：5

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