Synthesis and enantiomeric resolution of (±)-pinocembrin

被引：24

作者：

Yuan, Yue

Yang, Qing-Yun

Tong, Yuan-Feng

Chen, Feng

Qi, Yan

Duan, Ya-Bo

Wu, Song ^{[1
]}

机构：

[1] Peking Union Med Coll, Inst Mat Med, Beijing 100021, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2008年 / 10卷 / 10期

关键词：

pinocembrin; synthesis; enantiomeric resolution; chiral amine;

D O I：

10.1080/10286020802240418

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A convenient method for the synthesis and enantiomeric resolution of ()-pinocembrin has been developed. This route involves the hydrogenation of 5,7-dihydroxyflavone, the derivatization of racemic pinocembrin with chiral amine, and the separation of the diastereoisomers due to their different physical properties.

引用

页码：999 / 1002

页数：4

共 6 条

[1]

Pinocembrin chalcone:: An antibacterial compound from Helichrysum trilineatum [J].