1,5-α-D-Mannoseptanosides, Ring-Size Isomers That Are Impervious to α-Mannosidase-Catalyzed Hydrolysis

被引：32

作者：

Boone, Matthew A. ^{[1
]}

McDonald, Frank E. ^{[1
]}

Lichter, Joseph ^{[1
]}

Lutz, Stefan ^{[1
]}

Cao, Rui ^{[1
]}

Hardcastle, Kenneth I. ^{[1
]}

机构：

[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 04期

关键词：

O-ISOPROPYLIDENE DERIVATIVES; CARBOHYDRATE-BASED OXEPINES; XYLOSE-BASED OXEPINE; ALKYNOL CYCLOISOMERIZATION; ASYMMETRIC EPOXIDATION; D-GLUCOSEPTANOSIDE; IDOSEPTANOSIDE; CYCLIZATION; REACTIVITY; DIACETALS;

D O I：

10.1021/ol8028065

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,5-D-Mannoseptanosyl di- and trisaccharide ring-size isomers of the corresponding mannopyranosyl oligosaccharides have been prepared. Remarkably, these compounds show no inhibition of the alpha-mannosidase-catalyzed hydrolysis of p-nitrophenyl-alpha-D-mannopyranoside.

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页码：851 / 854

页数：4

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