Anticoagulants and pregnancy: When are they safe?

被引：25

作者：

Gibson, Paul S. ^{[1
,2
]}

Powrie, Raymond ^{[3
]}

机构：

[1] Univ Calgary, Dept Med, Calgary, AB T2N 1N4, Canada

[2] Univ Calgary, Dept Obstet & Gynaecol, Calgary, AB T2N 1N4, Canada

[3] Brown Univ, Women & Infants Hosp, Warren Alpert Med Sch, Providence, RI USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2009年 / 76卷 / 02期

关键词：

MOLECULAR-WEIGHT HEPARIN; MECHANICAL HEART-VALVES; DEEP-VEIN THROMBOSIS; LOW-DOSE ASPIRIN; BONE-MINERAL DENSITY; FACTOR-V-LEIDEN; UNFRACTIONATED HEPARIN; VENOUS THROMBOEMBOLISM; PULMONARY-EMBOLISM; INDUCED THROMBOCYTOPENIA;

D O I：

10.3949/ccjm.75a.072272

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Prescribing anticoagulants to pregnant women can be difficult and stressful. Fortunately, low-molecular-weight heparins (LMWHs) and unfractionated heparin are quite safe and efficacious when properly selected, dosed, and monitored. Maternal and fetal concerns must be considered at all times, with a careful assessment of the risks and benefits of anticoagulant therapy in each patient. Further research should help to clarify who should receive thromboprophylaxis, how to prevent adverse pregnancy outcomes in women with various thrombophilias, and how best to treat pregnant women who have a prosthetic heart valve.

引用

页码：113 / 127

页数：15

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