Effect of catheter placement on 3-D velocity profiles in curved tubes resembling the human coronary system

被引:28
作者
Krams, R
Wentzel, JJ
Cespedes, I
Vinke, R
Carlier, S
van der Steen, AFW
Lancee, CT
Slager, CJ
机构
[1] Erasmus Univ, Dept Hemodynam, Thoraxctr, Lab Hemodynam, Rotterdam, Netherlands
[2] Erasmus Univ, Thoraxctr, Lab Expt Echocardiog, NL-3000 DR Rotterdam, Netherlands
[3] ICIN, Utrecht, Netherlands
[4] Endoson Corp, Rancho Cordova, CA USA
关键词
CFD; catheter placement; coronary artery; shear stress;
D O I
10.1016/S0301-5629(99)00018-6
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Novel measurement techniques based on intravenous ultrasound (IVUS) technology ('IVUS-Flowmetry') require the location of a catheter inside the coronary bed. The present study quantifies disturbances in the 3-D velocity profile induced by catheter placement inside a tube, applying computational fluid dynamics. Two curved, circular meshes (radius K = 0.025 m and K = 0.035 m) with and without a catheter inside the lumen were applied. The catheter was located at the inner curve, the outer curve and at the top position. Boundary conditions were: no slip on the wall, zero stress at the outlet, uniform inflow with entrance velocities of 0,1, 0.2 and 0.4 m/s, Curvature-associated centrifugal forces shifted the maximal velocity to the outer curve and introduced two symmetrical vortices. Additional catheter placement redistributed the 3-D axial velocity field away from the catheter, which was accompanied by the appearance of multiple low-strength vortices. In addition, peak axial velocity increased, peak secondary velocities decreased, axial pressure drop increased and shear stress increased. Flow calculations simulated to resemble IVUS-based flowmetry changed by only 1% after considering secondary velocity. In conclusion, placement of a catheter inside a curved tube resembling the human coronary system changes the velocity field and reduces secondary patterns. The present study supports the usefulness of catbeter-based flowmetry during resting flow conditions. During hyperemic flow conditions, flow measurements might be accompanied by large axial pressure drops because the catheter, itself, might act as a significant stenosis, (C) 1999 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:803 / 810
页数:8
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